H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

<p>Abstract</p> <p>Background</p> <p>Endogenous retroviruses (ERVs) are parasitic sequences whose derepression is associated with cancer and genomic instability. Many ERV families are silenced in mouse embryonic stem cells (mESCs) via SETDB1-deposited trimethylated lysi...

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Bibliographic Details
Main Authors: Maksakova Irina A, Goyal Preeti, Bullwinkel Jörn, Brown Jeremy P, Bilenky Misha, Mager Dixie L, Singh Prim B, Lorincz Matthew C
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Epigenetics & Chromatin
Subjects:
endogenous retrovirus
ERV
heterochromatin protein 1
HP1
<it>Cbx1</it>
<it>Cbx3</it>
<it>Cbx5</it>
H3K9me3
retroviral repression
transcriptional silencing
mouse embryonic stem cells
Online Access:http://www.epigeneticsandchromatin.com/content/4/1/12

Internet

http://www.epigeneticsandchromatin.com/content/4/1/12

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