OSCA: a tool for omic-data-based complex trait analysis

Abstract The rapid increase of omic data has greatly facilitated the investigation of associations between omic profiles such as DNA methylation (DNAm) and complex traits in large cohorts. Here, we propose a mixed-linear-model-based method called MOMENT that tests for association between a DNAm prob...

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Bibliographic Details
Main Authors: Futao Zhang, Wenhan Chen, Zhihong Zhu, Qian Zhang, Marta F. Nabais, Ting Qi, Ian J. Deary, Naomi R. Wray, Peter M. Visscher, Allan F. McRae, Jian Yang
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-019-1718-z