Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases

Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases

The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that promote ligand-dependent transcription of target genes that regulate energy production, lipid metabolism, and inflammation. The PPAR superfamily comprises three subtypes, PPARα, PPARγ, and PPARβ/δ,...

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Bibliographic Details
Main Authors: Juan Decara, Patricia Rivera, Antonio Jesús López-Gambero, Antonia Serrano, Francisco Javier Pavón, Elena Baixeras, Fernando Rodríguez de Fonseca, Juan Suárez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Pharmacology
Subjects:
PPARα
PPARγ
PPARβ/δ
inflammatory bowel diseases
ulcerative colitis
Crohn's disease
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00730/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00730/full

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