Abnormal Topology of the Structural Connectome in the Limbic Cortico-Basal-Ganglia Circuit and Default-Mode Network Among Primary Insomnia Patients

Abnormal Topology of the Structural Connectome in the Limbic Cortico-Basal-Ganglia Circuit and Default-Mode Network Among Primary Insomnia Patients

Purpose: Primary insomnia (PI) is the second most common mental disorder. However, the topologic alterations in structural brain connectome in patients with PI remain largely unknown.Methods: A total of 44 PI patients and 46 age-, gender-, and education level matched healthy control (HC) participant...

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Bibliographic Details
Main Authors: Yunfan Wu, Mengchen Liu, Shaoqing Zeng, Xiaofen Ma, Jianhao Yan, Chulan Lin, Guang Xu, Guomin Li, Yi Yin, Shishun Fu, Kelei Hua, Chao Li, Tianyue Wang, Cheng Li, Guihua Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neuroscience
Subjects:
primary insomnia
diffusion tensor imaging
human connectome
fMRI
limbic system
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00860/full

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https://www.frontiersin.org/article/10.3389/fnins.2018.00860/full

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