Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease

Application of expanded genetic analysis in the diagnosis of familial hypercholesterolemia in patients with very early-onset coronary artery disease

Abstract Background Patients with monogenic familial hypercholesterolemia (FH) have high risk for coronary artery disease (CAD). A recent FH Expert Panel suggested that FH was underdiagnosed and undertreated which needs early diagnosis. Moreover, the proportion of DNA-confirmed FH patients hospitali...

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Bibliographic Details
Main Authors: Ye-Xuan Cao, Na-Qiong Wu, Di Sun, Hui-Hui Liu, Jing-Lu Jin, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Ying Gao, Qiu-Ting Dong, Geng Liu, Qian Dong, Jian-Jun Li
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Journal of Translational Medicine
Subjects:
Familial hypercholesterolemia
Genetic testing
Very early-onset CAD
Online Access:http://link.springer.com/article/10.1186/s12967-018-1737-7

Internet

http://link.springer.com/article/10.1186/s12967-018-1737-7

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