Metabolomic profiling identifies pathways associated with minimal residual disease in childhood acute lymphoblastic leukaemia

Background: End-induction minimal residual disease (MRD) is the strongest predictor of relapse in paediatric acute lymphoblastic leukaemia (ALL), but an understanding of the biological pathways underlying early treatment response remains elusive. We hypothesized that metabolomic profiling of diagnos...

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Bibliographic Details
Main Authors: Jeremy M. Schraw, Jacob J. Junco, Austin L. Brown, Michael E. Scheurer, Karen R. Rabin, Philip J. Lupo
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419306607