Limitations of Clinical Application of siRNA Delivery Based on Non-Viral Vectors

In recent years, much more attentions have been focused on siRNA-based gene therapy. This approach is based on PTGS (Post-transcriptional gene silencing). Due to some defects in viral vectors, non-viral vectors have been used to deliver nucleic acids into target cells. Although, transfection efficie...

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Bibliographic Details
Main Authors: Reza Ghavimi, Meraj Pourhossein
Format: Article
Language:fas
Published: Vesnu Publications 2014-04-01
Series:مجله دانشکده پزشکی اصفهان
Subjects:
Online Access:http://jims.mui.ac.ir/index.php/jims/article/view/3276