Synthesis, anticancer and antibacterial evaluation of novel (isopropylidene) uridine-[1,2,3]triazole hybrids

Synthesis, anticancer and antibacterial evaluation of novel (isopropylidene) uridine-[1,2,3]triazole hybrids

A series of novel (isopropylidene) uridine-[1,2,3]triazole hybrids (3a–3n) were efficiently synthesized via the copper-catalyzed azide–alkyne cycloaddition (CuAAC) from N-propargyl 2′,3′-O-(isopropylidene) uridine with different aryl azides. All the synthesized compounds were screened for their in v...

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Bibliographic Details
Main Authors: Ranjith kumar Thatipamula, Sirassu Narsimha, Kumaraswamy Battula, V. Rajendra Chary, Estari Mamidala, Nagavelli Vasudeva Reddy
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Journal of Saudi Chemical Society
Subjects:
Uridine
1,2,3-Triazole
Anticancer
Antibacterial activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610315001428

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http://www.sciencedirect.com/science/article/pii/S1319610315001428

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