Granulocytic myeloid-derived suppressor cells inhibit T follicular helper cells during experimental Schistosoma japonicum infection

Abstract Background CD4+ T helper (Th) cells play critical roles in both host humoral and cellular immunity against parasitic infection and in the immunopathology of schistosomiasis. T follicular helper (Tfh) cells are a specialized subset of Th cells involved in immunity against infectious diseases...

Full description

Bibliographic Details
Main Authors: Yumei Zhang, Yulong Wu, Hua Liu, Wenci Gong, Yuan Hu, Yujuan Shen, Jianping Cao
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Parasites & Vectors
Subjects:
Online Access:https://doi.org/10.1186/s13071-021-05006-8