Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells

Neferine Promotes GLUT4 Expression and Fusion With the Plasma Membrane to Induce Glucose Uptake in L6 Cells

Glucose transporter 4 (GLUT4) is involved in regulating glucose uptake in striated muscle, liver, and adipose tissue. Neferine is a dibenzyl isoquinoline alkaloid derived from dietary lotus seeds and has multiple pharmacological effects. Therefore, this study investigated neferine’s role in glucose...

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Bibliographic Details
Main Authors: Ping Zhao, Di Tian, Guanjun Song, Qian Ming, Jia Liu, Jinhua Shen, Qing-Hua Liu, Xinzhou Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
neferine
glucose transporter 4
Ca2+
L6 cells
type 2 diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00999/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00999/full

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