Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal

Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal

Analyses of gene expression in single mouse embryonic stem cells (mESCs) cultured in serum and LIF revealed the presence of two distinct cell subpopulations with individual gene expression signatures. Comparisons with published data revealed that cells in the first subpopulation are phenotypically s...

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Bibliographic Details
Main Authors: Dmitri Papatsenko, Henia Darr, Ivan V. Kulakovskiy, Avinash Waghray, Vsevolod J. Makeev, Ben D. MacArthur, Ihor R. Lemischka
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115002106

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http://www.sciencedirect.com/science/article/pii/S2213671115002106

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