Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathways.

<h4>Background</h4>The U12-type spliceosome is responsible for the removal of a subset of introns from eukaryotic mRNAs. U12-type introns are spliced less efficiently than normal U2-type introns, which suggests a rate-limiting role in gene expression. The Drosophila genome contains about...

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Bibliographic Details
Main Authors: Heli K J Pessa, Dario Greco, Jouni Kvist, Gudrun Wahlström, Tapio I Heino, Petri Auvinen, Mikko J Frilander
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20949011/?tool=EBI