Gut Microbial Changes in Diabetic db/db Mice and Recovery of Microbial Diversity upon Pirfenidone Treatment

Gut Microbial Changes in Diabetic db/db Mice and Recovery of Microbial Diversity upon Pirfenidone Treatment

The leptin receptor-deficient db/db mouse model is an accepted in vivo model to study obesity, type 2 diabetes, and diabetic kidney disease. Healthy gastrointestinal (GI) microbiota has been linked to weight loss, improved glycemic control, and physiological benefits. We investigated the effect of v...

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Bibliographic Details
Main Authors: Harinder Singh, Satoshi Miyamoto, Manjula Darshi, Manolito G. Torralba, Keehwan Kwon, Kumar Sharma, Rembert Pieper
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
gut microbiome
db/db mouse model
pirfenidone
cholecystokinin
type 2 diabetes
diabetic nephropathy
Online Access:https://www.mdpi.com/2076-2607/8/9/1347

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https://www.mdpi.com/2076-2607/8/9/1347

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