Increased Expression and Activation of FAK in Small-Cell Lung Cancer Compared to Non-Small-Cell Lung Cancer

Increased Expression and Activation of FAK in Small-Cell Lung Cancer Compared to Non-Small-Cell Lung Cancer

Introduction: Focal adhesion kinase (FAK) plays a crucial role in cancer development and progression. FAK is overexpressed and/or activated and associated with poor prognosis in various malignancies. However, in lung cancer, activated FAK expression and its prognostic value are unknown. Methods: FAK...

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Bibliographic Details
Main Authors: Frank Aboubakar Nana, Delphine Hoton, Jérôme Ambroise, Marylène Lecocq, Marie Vanderputten, Yves Sibille, Bart Vanaudenaerde, Charles Pilette, Caroline Bouzin, Sebahat Ocak
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
expression
fak
lung cancer
small-cell lung cancer
non-small-cell lung cancer
multiplex immunofluorescence staining
phospho-fak
prognosis
targeted therapy
Online Access:https://www.mdpi.com/2072-6694/11/10/1526

Internet

https://www.mdpi.com/2072-6694/11/10/1526

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