Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice

<p>Abstract</p> <p>Background</p> <p>Amiloride derivatives, commonly used for their diuretic and antihypertensive properties, can also cause a sustained but reversible decrease of intracellular pH (pH<sub>i</sub>). Using dimethyl amiloride (DMA) on normal ro...

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Bibliographic Details
Main Authors: Head W Steven, Gunawardana Subhadra C, Piston David W
Format: Article
Language:English
Published: BMC 2005-12-01
Series:BMC Endocrine Disorders
Online Access:http://www.biomedcentral.com/1472-6823/5/9