Histone deacetylase 1 interacts with HIV-1 Integrase and modulates viral replication

Histone deacetylase 1 interacts with HIV-1 Integrase and modulates viral replication

Abstract Background HIV-1 hijacks the cellular machinery for its own replication through protein-protein interactions between viral and host cell factors. One strategy against HIV-1 infection is thus to target these key protein complexes. As the integration of reverse transcribed viral cDNA into a h...

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Bibliographic Details
Main Authors: Fadila Larguet, Clément Caté, Benoit Barbeau, Eric Rassart, Elsy Edouard
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Virology Journal
Subjects:
HIV-1
Integrase
HDAC1
Preintegration step
Online Access:http://link.springer.com/article/10.1186/s12985-019-1249-y

Internet

http://link.springer.com/article/10.1186/s12985-019-1249-y

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