West Nile virus genetic diversity is maintained during transmission by Culex pipiens quinquefasciatus mosquitoes.

Due to error-prone replication, RNA viruses exist within hosts as a heterogeneous population of non-identical, but related viral variants. These populations may undergo bottlenecks during transmission that stochastically reduce variability leading to fitness declines. Such bottlenecks have been docu...

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Bibliographic Details
Main Authors: Doug E Brackney, Kendra N Pesko, Ivy K Brown, Eleanor R Deardorff, Jon Kawatachi, Gregory D Ebel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3171416?pdf=render