Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

RNA viruses compartmentalize their replication machinery to evade detection by host pattern recognition receptors and concentrate the machinery of RNA synthesis. For positive-strand RNA viruses, RNA replication occurs in a virus-induced membrane-associated replication organelle. For NNS RNA viruses,...

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Bibliographic Details
Main Authors: Bianca S. Heinrich, Zoltan Maliga, David A. Stein, Anthony A. Hyman, Sean P. J. Whelan
Format: Article
Language:English
Published: American Society for Microbiology 2018-09-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.02290-17