A kinetically controlled platform for ligand-oligonucleotide transduction

Ligand-oligonucleotide interactions can integrate both small molecules and proteins into nucleic acid-based circuits. Here the authors design ligand-aptamer complexes to control strand-displacement reactions for versatile ligand transduction.

Bibliographic Details
Main Authors: Qiu-Long Zhang, Liang-Liang Wang, Yan Liu, Jiao Lin, Liang Xu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24962-4