Patient Stratification of Clear Cell Renal Cell Carcinoma Using the Global Transcription Factor Activity Landscape Derived From RNA-Seq Data

Patient Stratification of Clear Cell Renal Cell Carcinoma Using the Global Transcription Factor Activity Landscape Derived From RNA-Seq Data

Clear cell renal cell carcinoma represents the most common type of kidney cancer. Precision medicine approach to ccRCC requires an accurate stratification of patients that can predict prognosis and guide therapeutic decision. Transcription factors are implicated in the initiation and progression of...

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Bibliographic Details
Main Authors: Yanyan Zhu, Shundong Cang, Bowang Chen, Yue Gu, Miaomiao Jiang, Junya Yan, Fengmin Shao, Xiaoyun Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
ccRCC
RNA-Seq
transcription factor
Systems Biology
personalized oncology
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.526577/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.526577/full

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