The regulation of CD4+ T cell responses during protozoan infections.

CD4+ T cells are critical for defence against protozoan parasites. Intracellular protozoan parasite infections generally require the development of a Th1 cell response, characterised by the production of IFNγ and TNF that are critical for the generation of microbiocidal molecules by phagocytes, as w...

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Bibliographic Details
Main Authors: Christian eEngwerda, Susanna S Ng, Patrick T Bunn
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00498/full