Adenosine A2A receptors and A2A receptor heteromers as key players in striatal function

Adenosine A2A receptors and A2A receptor heteromers as key players in striatal function

A very significant density of adenosine adenosine A2A receptors (A2ARs) is present in the striatum, where they are preferentially localized postsynaptically in striatopallidal medium spiny neurons (MSNs). In this localization A2ARs establish reciprocal antagonistic interactions with dopamine D2 rece...

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Bibliographic Details
Main Authors: Sergi eFerre, Cesar eQuiroz, Marco eOrru, Xavier eGuitart, Gema eNavarro, Antonio eCortes, Vicent eCasado, Enric I Canela, Carme eLluis, Rafael eFranco
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-06-01
Series:Frontiers in Neuroanatomy
Subjects:
Striatum
dopamine receptors
Adenosine A2A receptor
cannabinoid receptors
receptor heteromers
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2011.00036/full

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http://journal.frontiersin.org/Journal/10.3389/fnana.2011.00036/full

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