Defining the boundaries of species specificity for the Saccharomyces cerevisiae glycosylphosphatidylinositol transamidase using a quantitative in vivo assay

Defining the boundaries of species specificity for the Saccharomyces cerevisiae glycosylphosphatidylinositol transamidase using a quantitative in vivo assay

In eukaryotes, GPI (glycosylphosphatidylinositol) lipid anchoring of proteins is an abundant post-translational modification. The attachment of the GPI anchor is mediated by GPI-T (GPI transamidase), a multimeric, membrane-bound enzyme located in the ER (endoplasmic reticulum). Upon modification, GP...

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Bibliographic Details
Main Authors: Rachel Morissette, Yug Varma, Tamara L. Hendrickson
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-10-01
Series:Bioscience Reports
Subjects:
glycosylphosphatidylinositol anchoring
glycosylphosphatidylinositol transamidase
invertase
Saccharomyces cerevisiae
species specificity
Online Access:http://www.bioscirep.org/bsr/032/0577/bsr0320577.htm

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http://www.bioscirep.org/bsr/032/0577/bsr0320577.htm

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