New Insights in the Amyloid-Beta Interaction with Mitochondria

Biochemical and morphological alterations of mitochondria may play an important role in the pathogenesis of Alzheimer’s disease (AD). Particularly, mitochondrial dysfunction is a hallmark of amyloid-beta-induced neuronal toxicity in Alzheimer’s disease. The recent emphasis on the intracellular biolo...

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Bibliographic Details
Main Authors: Carlos Spuch, Saida Ortolano, Carmen Navarro
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.1155/2012/324968