Aerobic Glycolysis as a Marker of Tumor Aggressiveness: Preliminary Data in High Grade Human Brain Tumors

Objectives. Glucose metabolism outside of oxidative phosphorylation, or aerobic glycolysis (AG), is a hallmark of active cancer cells that is not directly measured with standard 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET). In this study, we characterized tumor regions with elevat...

Full description

Bibliographic Details
Main Authors: Andrei G. Vlassenko, Jonathan McConathy, Lars E. Couture, Yi Su, Parinaz Massoumzadeh, Hayden S. Leeds, Michael R. Chicoine, David D. Tran, Jiayi Huang, Sonika Dahiya, Daniel S. Marcus, Sarah Jost Fouke, Keith M. Rich, Marcus E. Raichle, Tammie L. S. Benzinger
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2015/874904