Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis

Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis

Abstract Background Liver fibrosis is an excessive wound-healing reaction that requires the participation of inflammatory cells and hepatic stellate cells (HSCs). The pathogenesis of liver fibrosis caused by viruses and alcohol has been well characterized, but the molecular mechanisms underlying liv...

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Bibliographic Details
Main Authors: Lina Zhou, Mengchen Shi, Lu Zhao, Zhipeng Lin, Zeli Tang, Hengchang Sun, Tingjin Chen, Zhiyue Lv, Jin Xu, Yan Huang, Xinbing Yu
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Parasites & Vectors
Subjects:
CsLysoPLA
Liver fibrosis
IL-25
Online Access:http://link.springer.com/article/10.1186/s13071-017-2228-z

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http://link.springer.com/article/10.1186/s13071-017-2228-z

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