Toward Quantitative Neurosurgical Guidance With High-Resolution Microscopy of 5-Aminolevulinic Acid-Induced Protoporphyrin IX

Toward Quantitative Neurosurgical Guidance With High-Resolution Microscopy of 5-Aminolevulinic Acid-Induced Protoporphyrin IX

Low-power fluorescence microscopy of 5-ALA-induced PpIX has emerged as a valuable intraoperative imaging technology for improving the resection of malignant gliomas. However, current fluorescence imaging tools are not highly sensitive nor quantitative, which limits their effectiveness for optimizing...

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Bibliographic Details
Main Authors: Linpeng Wei, Yoko Fujita, Nader Sanai, Jonathan T. C. Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Oncology
Subjects:
fluorescence-guided surgery
handheld microscopy
5-ALA
PpIX
gliomas
quantitative imaging
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00592/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00592/full

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