Low Serum Levels of DKK2 Predict Incident Low‐Impact Fracture in Older Women

Low Serum Levels of DKK2 Predict Incident Low‐Impact Fracture in Older Women

Abstract There are currently no robust noninvasive markers of fragility fractures. Secreted frizzled related protein‐1 (sFRP‐1), dickkopf‐related protein 1 (DKK1) and DKK2, and sclerostin (SOST) inhibit Wnt signaling and interfere with osteoblast‐mediated bone formation. We evaluated associations of...

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Bibliographic Details
Main Authors: Ana M Rodrigues, Mónica Eusébio, Ana B Rodrigues, Joana Caetano‐Lopes, Inês P Lopes, Ana Lopes, Jorge M Mendes, Pedro Simões Coelho, João Eurico Fonseca, Jaime C Branco, Helena Canhão
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:JBMR Plus
Subjects:
FRACTURE RISK ASSESSMENT
SCREENING
MOLECULAR PATHWAYS–REMODELING
Wnt/β‐CATENIN/LRPs
AGING
Online Access:https://doi.org/10.1002/jbm4.10179

Internet

https://doi.org/10.1002/jbm4.10179

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