Re-visiting the trans insertion model for complexin clamping

Re-visiting the trans insertion model for complexin clamping

We have previously proposed that complexin cross-links multiple pre-fusion SNARE complexes via a trans interaction to function as a clamp on SNARE-mediated neurotransmitter release. A recent NMR study was unable to detect the trans clamping interaction of complexin and therefore questioned the previ...

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Bibliographic Details
Main Authors: Shyam S Krishnakumar, Feng Li, Jeff Coleman, Curtis M Schauder, Daniel Kümmel, Frederic Pincet, James E Rothman, Karin M Reinisch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
membrane fusion
neurotransmitter
complexin
Online Access:https://elifesciences.org/articles/04463

Internet

https://elifesciences.org/articles/04463

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