Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMα peptides

The phenol-soluble modulin PSMα3 secreted by Staphylococcus aureus forms cross-α amyloid-like fibrils. Here the authors reveal the amyloid polymorphism of PSMs by presenting the cross-β amyloid fibril structures of the biofilm-associated PSMα1 and PSMα4 and showing that truncated PSMα3 antibacterial...

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Bibliographic Details
Main Authors: Nir Salinas, Jacques-Philippe Colletier, Asher Moshe, Meytal Landau
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05490-0