2,6-DMBQ is a novel mTOR inhibitor that reduces gastric cancer growth in vitro and in vivo

2,6-DMBQ is a novel mTOR inhibitor that reduces gastric cancer growth in vitro and in vivo

Abstract Background Fermented wheat germ extract has been reported to exert various pharmacological activities, including anti-oxidant, anti-cell growth and cell apoptosis in various cancer cells. Although 2,6-dimethoxy-1,4-benzoquinone (2,6-DMBQ) is a benzoquinone compound and found in fermented wh...

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Bibliographic Details
Main Authors: Xueyin Zu, Xiaoli Ma, Xiaomeng Xie, Bingbing Lu, Kyle Laster, Kangdong Liu, Zigang Dong, Dong Joon Kim
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
2,6-DMBQ
mTOR
p70S6K
Gastric cancer
Patient-derived xenograft
Online Access:http://link.springer.com/article/10.1186/s13046-020-01608-9

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http://link.springer.com/article/10.1186/s13046-020-01608-9

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