Error Analysis of Deep Sequencing of Phage Libraries: Peptides Censored in Sequencing

Next-generation sequencing techniques empower selection of ligands from phage-display libraries because they can detect low abundant clones and quantify changes in the copy numbers of clones without excessive selection rounds. Identification of errors in deep sequencing data is the most critical ste...

Full description

Bibliographic Details
Main Authors: Wadim L. Matochko, Ratmir Derda
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2013/491612