Targeting glutathione S-transferase M4 in Ewing sarcoma

Targeting glutathione S-transferase M4 in Ewing sarcoma

Ewing sarcoma is a malignant pediatric bone and soft tissue tumor. Although the 5-year survival rate of localized disease approaches 75%, the prognosis of metastatic and/or therapy-resistant disease remains dismal despite the wide use of aggressive therapeutic strategies. We previously reported that...

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Bibliographic Details
Main Authors: Rupeng eZhuo, kenneth ekosak, savita esankar, Elizabeth T Wiles, Ying eSun, Jianxing eZhang, Janet eAyello, Glenn ePrestwich, Paul eShami, Mitchell S Cairo, Stephen eLessnick, Wen eLuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-08-01
Series:Frontiers in Pediatrics
Subjects:
Drug Resistance
Ewing sarcoma
GSTM4
NBDHEX
JS-K
Online Access:http://journal.frontiersin.org/Journal/10.3389/fped.2014.00083/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fped.2014.00083/full

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