Parallelizable Microfluidic Platform to Model and Assess In Vitro Cellular Barriers: Technology and Application to Study the Interaction of 3D Tumor Spheroids with Cellular Barriers

Parallelizable Microfluidic Platform to Model and Assess In Vitro Cellular Barriers: Technology and Application to Study the Interaction of 3D Tumor Spheroids with Cellular Barriers

Endothelial and epithelial cellular barriers play a vital role in the selective transport of solutes and other molecules. The properties and function of these barriers are often affected in case of inflammation and disease. Modelling cellular barriers in vitro can greatly facilitate studies of infla...

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Bibliographic Details
Main Authors: Arya Lekshmi Nair, Lena Mesch, Ingo Schulz, Holger Becker, Julia Raible, Heiko Kiessling, Simon Werner, Ulrich Rothbauer, Christian Schmees, Marius Busche, Sebastian Trennheuser, Gert Fricker, Martin Stelzle
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biosensors
Subjects:
cellular barriers
microfluidic device
TEER
tumor spheroids
Fourier-transform impedance spectroscopy
Online Access:https://www.mdpi.com/2079-6374/11/9/314

Internet

https://www.mdpi.com/2079-6374/11/9/314

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