Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome

Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome

Rare pleiotropic genetic disorders, Ataxia-telangiectasia (A-T), Bloom syndrome (BS) and Nijmegen breakage syndrome (NBS) are characterised by immunodeficiency, extreme radiosensitivity, higher cancer susceptibility, premature aging, neurodegeneration and insulin resistance. Some of these functional...

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Bibliographic Details
Main Authors: Mateusz Maciejczyk, Bozena Mikoluc, Barbara Pietrucha, Edyta Heropolitanska - Pliszka, Malgorzata Pac, Radosław Motkowski, Halina Car
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231716303974

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http://www.sciencedirect.com/science/article/pii/S2213231716303974

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