Simultaneous Measurement of Urinary Trimethylamine (TMA) and Trimethylamine <i>N</i>-Oxide (TMAO) by Liquid Chromatography–Mass Spectrometry

Trimethylamine (TMA) is a gut microbial metabolite—rendered by the enzymatic cleavage of nutrients containing a TMA moiety in their chemical structure. TMA can be oxidized as trimethylamine <i>N</i>-oxide (TMAO) catalyzed by hepatic flavin monooxygenases. Circulating TMAO has been demons...

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Bibliographic Details
Main Authors: Xun Jia, Lucas J. Osborn, Zeneng Wang
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/8/1862