Pharmacokinetic and Pharmacodynamic Properties of Rosmarinic Acid in Rat Cholestatic Liver Injury

Pharmacokinetic and Pharmacodynamic Properties of Rosmarinic Acid in Rat Cholestatic Liver Injury

The objective of this study was to evaluate the hepatoprotective and metabolic effects of rosmarinic acid (RA) in rats. RA [100 mg/kg body weight (BW)] was intragastrically (i.g.) administered to Sprague-Dawley (SD) rats once a day for seven consecutive days. The rats were then i.g. administered &am...

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Bibliographic Details
Main Authors: Jianbin Min, Hao Chen, Zipeng Gong, Xian Liu, Tian Wu, Weirong Li, Jiansong Fang, Tianlai Huang, Yingfeng Zhang, Wei Zhao, Chenchen Zhu, Qi Wang, Suiqing Mi, Ningsheng Wang
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Molecules
Subjects:
rosmarinic acid
cholestasis
pharmacodynamics
pharmacokinetics
Online Access:http://www.mdpi.com/1420-3049/23/9/2287

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http://www.mdpi.com/1420-3049/23/9/2287

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