A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology

A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology

The current inability of clinical criteria to accurately identify the “at-risk group” for Amyotrophic Lateral Sclerosis (ALS) development as well as its unknown etiology are fueling the interest in biomarkers aimed at completing clinical approaches for the diagnosis. The Glial cell line-derived neur...

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Bibliographic Details
Main Authors: Serena Stanga, Liliana Brambilla, Bernadette Tasiaux, Anh H. Dang, Adrian Ivanoiu, Jean-Noël Octave, Daniela Rossi, Vincent van Pesch, Pascal Kienlen-Campard
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neurology
Subjects:
biomarker
neurodegeneration
glial cell line-derived neurotrophic factor (GDNF)
amyloid precursor protein (APP)
amyotrophic lateral sclerosis (ALS)
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00384/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.00384/full

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