Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques

Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques

Analyses of human clinical HIV-1 vaccine trials and preclinical vaccine studies performed in rhesus macaque (RM) models have identified associations between non-neutralizing Fc Receptor (FcR)-dependent antibody effector functions and reduced risk of infection. Specifically, antibody-dependent phagoc...

Full description

Bibliographic Details
Main Authors: Justin Pollara, Matthew Zirui Tay, R. Whitney Edwards, Derrick Goodman, Andrew R. Crowley, Robert J. Edwards, David Easterhoff, Haleigh E. Conley, Taylor Hoxie, Thaddeus Gurley, Caroline Jones, Emily Machiele, Marina Tuyishime, Elizabeth Donahue, Shalini Jha, Rachel L. Spreng, Thomas J. Hope, Kevin Wiehe, Max M. He, M. Anthony Moody, Kevin O. Saunders, Margaret E. Ackerman, Guido Ferrari, Georgia D. Tomaras
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
phagocytosis
Fc Receptor
rhesus macaques
antibody function
IgG3
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.678511/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.678511/full

Similar Items