Bioabsorbable bypass grafts biofunctionalised with RGD have enhanced biophysical properties and endothelialisation tested in vivo

Bioabsorbable bypass grafts biofunctionalised with RGD have enhanced biophysical properties and endothelialisation tested in vivo

Small diameter arterial bypass grafts are considered as unmet clinical need since the current grafts have poor patency of 25% within 5 years. We have developed a 3D scaffold manufactured from natural and synthetic biodegradable polymers, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and poly(ε...

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Bibliographic Details
Main Authors: Larisa V Antonova, Anton G. Kutikhin, Alexander Marcus Seifalian, Victoria V Sevostyanova, Evgeniya O Krivkina, Andrey V Mironov, Andrey Yu Burago, Elena A Velikanova, Vera G Matveeva, Tatiana V Glushkova, Evgeniya A Sergeeva, Georgiy Yu Vasyukov, Yuliya A Kudryavtseva, Olga L Barbarash, Leonid S Barbarash
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Pharmacology
Subjects:
morphology
Biocompatibility
Poly(e-caprolactone)
poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
vascular grafts
Physico-mechanical properties
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00136/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00136/full

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