Mitochondrial dynamics protein Drp1 is overexpressed in oncocytic thyroid tumors and regulates cancer cell migration.

Oncocytic cell tumors are characterized by the accumulation of morphologically abnormal mitochondria in their cells, suggesting a role for abnormal mitochondrial biogenesis in oncocytic cell transformation. Little is known about the reason for the dysmorphology of accumulated mitochondria. The prote...

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Bibliographic Details
Main Authors: André Ferreira-da-Silva, Cristina Valacca, Elisabete Rios, Helena Pópulo, Paula Soares, Manuel Sobrinho-Simões, Luca Scorrano, Valdemar Máximo, Silvia Campello
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4379140?pdf=render