Effects of Osmolality on Paracellular Transport in MDCK II Cells.

Epithelia separate apical and basal compartments, and movement of substances via the paracellular pathway is regulated by tight junctions. Claudins are major constituents of tight junctions and involved in the regulation of tight junction permeability. On the other hand, the osmolality in the extrac...

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Bibliographic Details
Main Authors: Shinsaku Tokuda, Toyohiro Hirai, Mikio Furuse
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5113991?pdf=render