Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring.

Subclinical in utero Zika virus infection is associated with interferon alpha sequelae and sex-specific molecular brain pathology in asymptomatic porcine offspring.

Zika virus (ZIKV) infection during human pregnancy may lead to severe fetal pathology and debilitating impairments in offspring. However, the majority of infections are subclinical and not associated with evident birth defects. Potentially detrimental life-long health outcomes in asymptomatic offspr...

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Bibliographic Details
Main Authors: Ivan Trus, Daniel Udenze, Brian Cox, Nathalie Berube, Rebecca E Nordquist, Franz Josef van der Staay, Yanyun Huang, Gary Kobinger, David Safronetz, Volker Gerdts, Uladzimir Karniychuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008038

Internet

https://doi.org/10.1371/journal.ppat.1008038

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