IL-10-Dependent Amelioration of Chronic Inflammatory Disease by Microdose Subcutaneous Delivery of a Prototypic Immunoregulatory Small Molecule

IL-10-Dependent Amelioration of Chronic Inflammatory Disease by Microdose Subcutaneous Delivery of a Prototypic Immunoregulatory Small Molecule

One of the interventional strategies to reestablish the immune effector/regulatory balance, that is typically altered in chronic inflammatory diseases (CID), is the reinforcement of endogenous immunomodulatory pathways as the one triggered by interleukin (IL)-10. In a recent work, we demonstrated th...

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Bibliographic Details
Main Authors: Jorge H. Tabares-Guevara, Julio C. Jaramillo, Laura Ospina-Quintero, Christian A. Piedrahíta-Ochoa, Natalia García-Valencia, David E. Bautista-Erazo, Erika Caro-Gómez, Camila Covián, Angello Retamal-Díaz, Luisa F. Duarte, Pablo A. González, Susan M. Bueno, Claudia A. Riedel, Alexis M. Kalergis, José R. Ramírez-Pineda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Interleukin-10
atherosclerosis
experimental autoimmune encephalomyelitis
chronic inflammatory disease
immune regulation
curcumin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.708955/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.708955/full

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