Human papillomavirus 16 (HPV16) enhances tumor growth and cancer stemness of HPV-negative oral/oropharyngeal squamous cell carcinoma cells via miR-181 regulation

High-risk human papillomaviruses (e. g., HPV16, HPV18) are closely associated with the development of head and neck cancers including oral/oropharyngeal squamous cell carcinoma (OSCC). We previously demonstrated immortalization of normal human oral keratinocytes by introducing high-risk HPV whole ge...

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Bibliographic Details
Main Authors: Sung Hee Lee, Chang-Ryul Lee, Nicole Kristina Rigas, Reuben H. Kim, Mo K. Kang, No-Hee Park, Ki-Hyuk Shin
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Papillomavirus Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2405852115000142