The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.

The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.

Rapamycin is an anticancer agent and immunosuppressant that acts by inhibiting the TOR signaling pathway. In yeast, rapamycin mediates a profound transcriptional response for which the RRD1 gene is required. To further investigate this connection, we performed genome-wide location analysis of RNA po...

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Bibliographic Details
Main Authors: Jeremie Poschmann, Simon Drouin, Pierre-Etienne Jacques, Karima El Fadili, Michael Newmarch, François Robert, Dindial Ramotar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3160861?pdf=render

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http://europepmc.org/articles/PMC3160861?pdf=render

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