Myofiber androgen receptor increases muscle strength mediated by a skeletal muscle splicing variant of Mylk4

Summary: Androgens have a robust effect on skeletal muscles to increase muscle mass and strength. The molecular mechanism of androgen/androgen receptor (AR) action on muscle strength is still not well known, especially for the regulation of sarcomeric genes. In this study, we generated androgen-indu...

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Bibliographic Details
Main Authors: Iori Sakakibara, Yuta Yanagihara, Koichi Himori, Takashi Yamada, Hiroshi Sakai, Yuichiro Sawada, Hirotaka Takahashi, Noritaka Saeki, Hiroyuki Hirakawa, Atsushi Yokoyama, So-ichiro Fukada, Tatsuya Sawasaki, Yuuki Imai
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221002716