Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways.

As the interface between a microbe and its environment, the bacterial cell envelope has broad biological and clinical significance. While numerous biosynthesis genes and pathways have been identified and studied in isolation, how these intersect functionally to ensure envelope integrity during adapt...

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Bibliographic Details
Main Authors: Mohan Babu, J Javier Díaz-Mejía, James Vlasblom, Alla Gagarinova, Sadhna Phanse, Chris Graham, Fouad Yousif, Huiming Ding, Xuejian Xiong, Anaies Nazarians-Armavil, Md Alamgir, Mehrab Ali, Oxana Pogoutse, Asaf Pe'er, Roland Arnold, Magali Michaut, John Parkinson, Ashkan Golshani, Chris Whitfield, Shoshana J Wodak, Gabriel Moreno-Hagelsieb, Jack F Greenblatt, Andrew Emili
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3219608?pdf=render