GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme

GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme

Glycoprotein A repetition predominant (GARP), a specific surface molecule of activated regulatory T cells, has been demonstrated to significantly contribute to tolerance in humans by induction of peripheral Treg and regulatory M2-macrophages and by inhibition of (tumorantigen-specific) T effector ce...

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Bibliographic Details
Main Authors: Niklas Zimmer, Ella Kim, Jonathan Schupp, Bettina Sprang, Petra Leukel, Fatemeh Khafaji, Florian Ringel, Clemens Sommer, Jochen Tuettenberg, Andrea Tuettenberg
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
glioblastoma
GARP
tumor microenvironment
immunotherapy
regulatory T cells
Online Access:https://www.mdpi.com/1422-0067/20/15/3676

Internet

https://www.mdpi.com/1422-0067/20/15/3676

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