Evidence for a non-canonical JAK/STAT signaling pathway in the synthesis of the brain’s major ion channels and neurotransmitter receptors

Evidence for a non-canonical JAK/STAT signaling pathway in the synthesis of the brain’s major ion channels and neurotransmitter receptors

Abstract Background Brain-derived neurotrophic factor (BDNF) is a major signaling molecule that the brain uses to control a vast network of intracellular cascades fundamental to properties of learning and memory, and cognition. While much is known about BDNF signaling in the healthy nervous system w...

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Bibliographic Details
Main Authors: Kathryn M. Hixson, Meaghan Cogswell, Amy R. Brooks-Kayal, Shelley J. Russek
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Genomics
Subjects:
JAK/STAT
Neurons
RNAseq
BDNF
HP1α
Epilepsy
Online Access:http://link.springer.com/article/10.1186/s12864-019-6033-2

Internet

http://link.springer.com/article/10.1186/s12864-019-6033-2

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